产品名称
TRI35 Rabbit Polyclonal Antibody
基因名称
TRIM35 HLS5 KIAA1098
蛋白名称
Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UPQ4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UPQ4/entry
Mouse Swissprot No.
Q8C006
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C006
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5RKG6
免疫原
Synthesized peptide derived from human protein . at AA range: 320-400
特异性
TRI35 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity). .
功能
domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
