产品名称
MSMO1 Rabbit Polyclonal Antibody
基因名称
MSMO1 DESP4 ERG25 SC4MOL
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6307
Human Swissprot No.
Q15800
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15800/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/66234
Mouse Swissprot No.
Q9CRA4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CRA4
Rat Gene Link
https://www.uniprot.org/uniprot/140910
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O35532
免疫原
Synthesized peptide derived from human MSMO1 AA range: 212-262
特异性
This antibody detects endogenous levels of MSMO1 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
catalytic activity:3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate + NAD(P)(+) + H(2)O.,catalytic activity:4,4-dimethyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)(+) + H(2)O.,catalytic activity:4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)(+) + 2 H(2)O.,cofactor:Iron.,domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,pathway:Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 3/6.,similarity:Belongs to the sterol desaturase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
