产品名称
CLCB Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1212
Human Swissprot No.
P09497
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P09497/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74325
Mouse Swissprot No.
Q6IRU5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IRU5
Rat Gene Link
https://www.uniprot.org/uniprot/116561
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P08082
免疫原
Synthesized peptide derived from human CLCB AA range: 168-218
特异性
This antibody detects endogenous levels of CLCB at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles.
功能
function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.,subcellular location:Cytoplasmic face of coated pits and vesicles.,subunit:Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
