产品名称
SASH1 Rabbit Polyclonal Antibody
基因名称
SASH1 KIAA0790 PEPE1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23328
Human Swissprot No.
O94885
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O94885/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/70097
Mouse Swissprot No.
P59808
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P59808
免疫原
Synthesized peptide derived from human SASH1 AA range: 373-423
特异性
This antibody detects endogenous levels of SASH1 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues. Expressed in the epidermis, epidermal keratinocytes, dermal fibroblasts and melanocytes (PubMed:23333244, PubMed:26203640).
功能
function:May have a role in a signaling pathway. Could act as a tumor suppressor.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,tissue specificity:Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
