产品名称
BMP2K Rabbit Polyclonal Antibody
基因名称
BMP2K BIKE HRIHFB2017
蛋白名称
BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NSY1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NSY1/entry
Mouse Swissprot No.
Q91Z96
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91Z96
免疫原
Synthesized peptide derived from human protein . at AA range: 740-820
特异性
BMP2K Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Brain,Epithelium,Ovary,Synovial membrane tissue,Testis,Thyroid,
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May be involved in osteoblast differentiation.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
