产品名称
BIN3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55909
Human Swissprot No.
Q9NQY0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQY0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/57784
Mouse Swissprot No.
Q9JI08
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JI08
Rat Gene Link
https://www.uniprot.org/uniprot/361065
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q68FW8
免疫原
Synthesized peptide derived from human BIN3 AA range: 184-234
特异性
This antibody detects endogenous levels of BIN3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitously expressed except in brain.
细胞定位
Cytoplasm, cytoskeleton.
功能
function:Involved in cytokinesis and septation where it has a role in the localization of F-actin.,similarity:Contains 1 BAR domain.,tissue specificity:Ubiquitously expressed except in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.