产品名称
VCX3 Rabbit Polyclonal Antibody
基因名称
VCX3A VCX3 VCX8R VCXA
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51481
Human Swissprot No.
Q9NNX9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NNX9/entry
免疫原
Synthesized peptide derived from human VCX3 AA range: 40-90
特异性
This antibody detects endogenous levels of VCX3 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008],
组织表达
Expressed exclusively in testis.
功能
disease:Defects in VCX3A are associated with some forms of X-linked nonspecific mental retardation.,function:May mediate a process in spermatogenesis or may play a role in sex ratio distortion.,similarity:Belongs to the VCX/VCY family.,tissue specificity:Expressed exclusively in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
