产品名称
RBM25 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/58517
Human Swissprot No.
P49756
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49756/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67039
Mouse Swissprot No.
B2RY56
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/B2RY56
免疫原
Synthesized peptide derived from human RBM25 AA range: 763-813
特异性
This antibody detects endogenous levels of RBM25 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
细胞定位
Nucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.
功能
PTM:Sumoylated.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 PWI domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Detected predominantly in nuclear speckles. Cytoplasmic localization is faint.,subunit:Interacts with SRRM1. Specifically associates with functional splicing complexes, including Sm proteins and U1, U2, U4, U5 and U6 snRNAs. Associates with exon junction complex (EJC) proteins, including APEX1, BAT1, NCBP1, RBM8A and RNPS1. Interaction with NCBP1 is RNA-dependent.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
