产品名称
PPR17 Rabbit Polyclonal Antibody
基因名称
PPP1R17 C7orf16 GSBS
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10842
Human Swissprot No.
O96001
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O96001/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/19051
Mouse Swissprot No.
Q9Z2E4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z2E4
免疫原
Synthesized peptide derived from human PPR17 AA range: 75-125
特异性
This antibody detects endogenous levels of PPR17 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010],
组织表达
Highly expressed in cerebellum.
功能
function:Inhibits protein phosphatase-2A and protein phosphatase-1.,PTM:Substrate for cGMP-dependent protein kinase.,tissue specificity:Highly expressed in cerebellum.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
