产品名称
H11 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3024
Human Swissprot No.
Q02539
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q02539/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/80838
Mouse Swissprot No.
P43275
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P43275
Rat Gene Link
https://www.uniprot.org/uniprot/291145
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4A3K5
免疫原
Synthesized peptide derived from human H11 AA range: 49-99
特异性
This antibody detects endogenous levels of H11 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],
细胞定位
Nucleus . Chromosome . Mainly localizes in euchromatin.
功能
function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.,similarity:Belongs to the histone H1/H5 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
