产品名称
FKB10 Rabbit Polyclonal Antibody
基因名称
FKBP10 FKBP65 PSEC0056
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/60681
Human Swissprot No.
Q96AY3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96AY3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/14230
Mouse Swissprot No.
Q61576
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61576
免疫原
Synthesized peptide derived from human FKB10 AA range: 339-389
特异性
This antibody detects endogenous levels of FKB10 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009],
细胞定位
Endoplasmic reticulum lumen .
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin, but not by cyclosporin A.,function:PPIases accelerate the folding of proteins during protein synthesis.,PTM:Glycosylated and phosphorylated.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 PPIase FKBP-type domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
