产品名称
TUSC1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/286319
Human Swissprot No.
Q2TAM9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2TAM9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69136
Mouse Swissprot No.
Q673H1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q673H1
免疫原
Synthesized peptide derived from human TUSC1 AA range: 120-170
特异性
This antibody detects endogenous levels of TUSC1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines.
功能
tissue specificity:Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
