产品名称
LCMT2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9836
Human Swissprot No.
O60294
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O60294/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/329504
Mouse Swissprot No.
Q8BYR1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BYR1
Rat Gene Link
https://www.uniprot.org/uniprot/296098
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIA3
免疫原
Synthesized peptide derived from human LCMT2 AA range: 298-348
特异性
This antibody detects endogenous levels of LCMT2 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008],
功能
function:Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.,pathway:tRNA modification; wybutosine-tRNA(Phe) biosynthesis.,similarity:Belongs to the methyltransferase superfamily. LCMT family.,subunit:Interacts with RNF144B/IBRDC2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
