产品名称
ATG12 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9140
Human Swissprot No.
O94817
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O94817/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67526
Mouse Swissprot No.
Q9CQY1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CQY1
Rat Gene Link
https://www.uniprot.org/uniprot/361321
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q2TBJ5
免疫原
Synthesized peptide derived from human ATG12 AA range: 80-130
特异性
This antibody detects endogenous levels of ATG12 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008],
细胞定位
Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.
功能
function:Required for autophagy.,similarity:Belongs to the ATG12 family.,subunit:Conjugated to ATG5.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
