产品名称
AMELY Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/266
Human Swissprot No.
Q99218
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99218/entry
免疫原
Synthesized peptide derived from human AMELY.AA range 17-57
特异性
This antibody detects endogenous levels of AMELY at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix.
功能
developmental stage:Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.,function:Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.,miscellaneous:This isoform is encoded on the Y chromosome.,similarity:Belongs to the amelogenin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
