产品名称
PI42C Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/79837
Human Swissprot No.
Q8TBX8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TBX8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/117150
Mouse Swissprot No.
Q91XU3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91XU3
Rat Gene Link
https://www.uniprot.org/uniprot/140607
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O88370
免疫原
Synthesized peptide derived from human PI42C AA range: 262-312
特异性
This antibody detects endogenous levels of PI42C at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
细胞定位
Endoplasmic reticulum . Cytoplasm .
功能
catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.,function:May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.,PTM:Phosphorylated.,similarity:Contains 1 PI5K domain.,subcellular location:Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.