产品名称
AL1L2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/160428
Human Swissprot No.
Q3SY69
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q3SY69/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/216188
Mouse Swissprot No.
Q8K009
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K009
免疫原
Synthesized peptide derived from human AL1L2 AA range: 74-124
特异性
This antibody detects endogenous levels of AL1L2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010],
组织表达
Highly expressed in pancreas, heart, brain and skeletal muscle.
功能
catalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,sequence caution:Wrong choice of CDS.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
