产品名称
GRCR1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/389207
Human Swissprot No.
A8MXD5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/A8MXD5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/433899
Mouse Swissprot No.
Q50H32
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q50H32
免疫原
Synthesized peptide derived from human GRCR1 AA range: 132-182
特异性
This antibody detects endogenous levels of GRCR1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010],
组织表达
Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea.
细胞定位
Cell projection, stereocilium . Cell projection, microvillus . Cell projection, kinocilium . In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. .
功能
similarity:Belongs to the GRXCR1 family.,similarity:Contains 1 glutaredoxin domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
