产品名称
NEUR2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4759
Human Swissprot No.
Q9Y3R4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y3R4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/23956
Mouse Swissprot No.
Q9JMH3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JMH3
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64627
免疫原
Synthesized peptide derived from human NEUR2 AA range: 69-119
特异性
This antibody detects endogenous levels of NEUR2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008],
组织表达
Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1.
细胞定位
Cytoplasm, cytosol .
功能
catalytic activity:Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.,function:Hydrolyzes sialylated compounds.,similarity:Belongs to the glycosyl hydrolase 33 family.,similarity:Contains 2 BNR repeats.,tissue specificity:Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2D1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
