产品名称
RN141 Rabbit Polyclonal Antibody
蛋白名称
RING finger protein 141 (Zinc finger protein 230)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WVD5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WVD5/entry
Mouse Swissprot No.
Q99MB7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99MB7
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6IV57
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
RN141 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ring finger protein 141(RNF141) Homo sapiens The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis. [provided by RefSeq, Jul 2008],
组织表达
Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients.
细胞定位
Membrane ; Lipid-anchor .
功能
function:May be involved in spermatogenesis.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
