产品名称
KR261 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/388818
Human Swissprot No.
Q6PEX3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PEX3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69533
Mouse Swissprot No.
Q9D7N2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D7N2
免疫原
Synthesized peptide derived from human KR261 AA range: 153-203
特异性
This antibody detects endogenous levels of KR261 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
组织表达
Localized high up in the well differentiated portion of the hair follicle cuticle (about 10-15 cell layers above the apex of the dermal papilla).
细胞定位
intermediate filament,
功能
function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Localized high up in the well differentiated portion of the hair follicle cuticle (about 10-15 cell layers above the apex of the dermal papilla).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.