产品名称
F19A4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/151647
Human Swissprot No.
Q96LR4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96LR4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/320701
Mouse Swissprot No.
Q7TPG5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TPG5
免疫原
Synthesized peptide derived from human F19A4 AA range: 40-90
特异性
This antibody detects endogenous levels of F19A4 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011],
组织表达
Expressed in brain (PubMed:15028294). Expressed in LPS-stimulated monocytes and macrophages, especially in polarized M1 (PubMed:25109685).
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,similarity:Belongs to the FAM19/TAFA family.,tissue specificity:Brain-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
