产品名称
QOR Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1429
Human Swissprot No.
Q08257
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q08257/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/12972
Mouse Swissprot No.
P47199
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P47199
Rat Gene Link
https://www.uniprot.org/uniprot/362061
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AYT0
免疫原
Synthesized peptide derived from human QOR AA range: 275-325
特异性
This antibody detects endogenous levels of QOR at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008],
组织表达
Only very low amounts in the lens.
功能
catalytic activity:NADPH + 2 quinone = NADP(+) + 2 semiquinone.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones are the best substrates. May act in the detoxification of xenobiotics.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homotetramer.,tissue specificity:Only very low amounts in the lens.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
