产品名称
ARL8B Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55207
Human Swissprot No.
Q9NVJ2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NVJ2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67166
Mouse Swissprot No.
Q9CQW2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CQW2
Rat Gene Link
https://www.uniprot.org/uniprot/500282
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q66HA6
免疫原
Synthesized peptide derived from human ARL8B AA range: 9-59
特异性
This antibody detects endogenous levels of ARL8B at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Ubiquitously expressed.
细胞定位
Late endosome membrane . Lysosome membrane . Cytoplasm, cytoskeleton, spindle . Cell projection, axon . Cell junction, synapse . Cytolytic granule membrane . GTP-bound form resides on lysosomal membranes, whereas GDP-bound form is likely associated with microtubular structures (PubMed:16650381). Localizes with microtubules at the spindle mid-zone during mitosis. In dendritic cells, localizes to MHC II+ compartments (By similarity). .
功能
function:May play a role in lysosomes motility (PubMed:16537643). May play a role in chromosomes segregation (PubMed:15331635).,similarity:Belongs to the small GTPase superfamily. Arf family.,subcellular location:According to PubMed:15331635 it localizes with microtubules at the spindle mid-zone during mitosis.,subunit:Interacts with tubulin.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
