产品名称
KR131 Rabbit Polyclonal Antibody
基因名称
KRTAP13-1 KAP13.1 KRTAP13.1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/140258
Human Swissprot No.
Q8IUC0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IUC0/entry
免疫原
Synthesized peptide derived from human KR131 AA range: 99-149
特异性
This antibody detects endogenous levels of KR131 at Human
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008],
组织表达
Weak expression seen in the late matrix and entire cortex area of the hair follicle.
细胞定位
intermediate filament,
功能
caution:The sequence of 1-41 of PubMed:12359730 has not been submitted.,function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Weak expression seen in the late matrix and entire cortex area of the hair follicle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
