产品名称
METK2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4144
Human Swissprot No.
P31153
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P31153/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/232087
Mouse Swissprot No.
Q3THS6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3THS6
Rat Gene Link
https://www.uniprot.org/uniprot/171347
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P18298
免疫原
Synthesized peptide derived from human METK2 AA range: 294-344
特异性
This antibody detects endogenous levels of METK2 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011],
细胞定位
cytosol,methionine adenosyltransferase complex,
功能
catalytic activity:ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine.,cofactor:Binds 1 potassium ion per subunit.,cofactor:Binds 2 divalent ions per subunit. Magnesium or cobalt.,function:Catalyzes the formation of S-adenosylmethionine from methionine and ATP.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,PTM:The alpha' subunit is a post-translationally modified version of MAT2A.,similarity:Belongs to the AdoMet synthetase family.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
