产品名称
IFFO1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/25900
Human Swissprot No.
Q0D2I5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q0D2I5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/320678
Mouse Swissprot No.
Q8BXL9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BXL9
免疫原
Synthesized peptide derived from human IFFO1 AA range: 387-437
特异性
This antibody detects endogenous levels of IFFO1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structurally related but have limited sequence homology, with the exception of the central rod domain. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010],
组织表达
Ubiquitously expressed.
细胞定位
Nucleus . Nucleus, nucleoplasm . Nucleus inner membrane . Nucleus matrix . Mainly soluble, the remaining is localized in the nuclear matrix (PubMed:31548606). Localized at double-strand break (DSB) sites near the lamina and nuclear matrix structures (PubMed:31548606). .
功能
similarity:Belongs to the intermediate filament family.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
