产品名称
ALG13 Rabbit Polyclonal Antibody
基因名称
ALG13 CXorf45 GLT28D1 MDS031
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/79868
Human Swissprot No.
Q9NP73
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NP73/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67574
Mouse Swissprot No.
Q9D8C3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D8C3
Rat Gene Link
https://www.uniprot.org/uniprot/300284
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5I0K7
免疫原
Synthesized peptide derived from human ALG13 AA range: 69-119
特异性
This antibody detects endogenous levels of ALG13 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
细胞定位
[Isoform 2]: Endoplasmic reticulum . Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14.
功能
catalytic activity:UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.,function:Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.,online information:GlycoGene database,similarity:Belongs to the glycosyltransferase 28 family.,subunit:Heterodimer with ALG14 to form a functional enzyme.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
