产品名称
PGFRL Rabbit Polyclonal Antibody
蛋白名称
Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15198
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15198/entry
Mouse Swissprot No.
Q6PE55
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6PE55
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5RJP7
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
PGFRL Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008],
组织表达
Expressed in colon, lung and liver.
功能
disease:Defects in PDGFRL are associated with colorectal cancer (CRC) [MIM:114500].,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in colon, lung and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.