产品名称
C99L2 Rabbit Polyclonal Antibody
基因名称
CD99L2 MIC2L1 UNQ1964/PRO4486
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/83692
Human Swissprot No.
Q8TCZ2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TCZ2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/171486
Mouse Swissprot No.
Q8BIF0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BIF0
Rat Gene Link
https://www.uniprot.org/uniprot/171485
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1R5
免疫原
Synthesized peptide derived from human C99L2 AA range: 204-254
特异性
This antibody detects endogenous levels of C99L2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
组织表达
Expressed in many tissues, with low expression in thymus.
细胞定位
Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell junction .
功能
function:May function as a homophilic adhesion molecule. Functions in leukocyte-endothelial cell interactions during leukocyte extravasation, and in particular, at the diapedesis step. Does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis.,PTM:O-glycosylated.,similarity:Belongs to the CD99 family.,tissue specificity:Expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis and uterus. Lower expression seen in thymus. Expressed in E18 uterus and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
