产品名称
TYY2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/404281
Human Swissprot No.
O15391
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15391/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/100073351
Mouse Swissprot No.
Q3TTC2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3TTC2
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C6P6
免疫原
Synthesized peptide derived from human TYY2 AA range: 9-59
特异性
This antibody detects endogenous levels of TYY2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010],
组织表达
Expressed in kidney, liver, spleen and testis but not in colon.
功能
function:Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.,miscellaneous:The gene encoding this protein appears to have arisen by retrotransposition of the YY1 gene in placental mammals. It is encoded by a single exon found in an intron of the gene Mbtps2.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in kidney, liver, spleen and testis but not in colon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
