产品名称
IRX5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10265
Human Swissprot No.
P78411
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P78411/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/54352
Mouse Swissprot No.
Q9JKQ4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JKQ4
免疫原
Synthesized peptide derived from human IRX5 AA range: 64-114
特异性
This antibody detects endogenous levels of IRX5 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
功能
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
