产品名称
NOCT Rabbit Polyclonal Antibody
蛋白名称
Nocturnin (CCR4 protein homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UK39
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UK39/entry
Mouse Swissprot No.
O35710
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35710
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9ET55
免疫原
Synthesized peptide derived from human protein . at AA range: 100-180
特异性
NOCT Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
nocturnin(NOCT) Homo sapiens The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008],
组织表达
Adipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue.
细胞定位
Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Mitochondrion .
功能
function:Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases.,similarity:Belongs to the CCR4/nocturin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
