BD-PT7024

PPIL1 Rabbit Polyclonal Antibody

常规抗体

PPIL1 CYPL1 CGI-124 UNQ2425/PRO4984

PPIL1

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

51645

https://www.uniprot.org/uniprot/51645

Q9Y3C6

https://www.uniprot.org/uniprotkb/Q9Y3C6/entry

68816

https://www.uniprot.org/uniprot/68816

Q9D0W5

https://www.uniprot.org/uniprotkb/Q9D0W5

Synthesized peptide derived from human PPIL1 AA range: 73-123

This antibody detects endogenous levels of PPIL1 at Human/Mouse

WB 1:500-2000;IHC-p 1:50-300

18kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008],

Ubiquitous, with the most abundant expression in heart and skeletal muscle.

Nucleus .

catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by Cyclosporin A.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.,similarity:Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.,similarity:Contains 1 PPIase cyclophilin-type domain.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,tissue specificity:Ubiquitous, with the most abundant expression in heart and skeletal muscle.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.