产品名称
PFD4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5203
Human Swissprot No.
Q9NQP4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQP4/entry
免疫原
Synthesized peptide derived from human PFD4 AA range: 65-115
特异性
This antibody detects endogenous levels of PFD4 at Human
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Mitochondrion .
功能
function:Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.,similarity:Belongs to the prefoldin subunit beta family.,subunit:Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
