产品名称
MTF1 Rabbit Polyclonal Antibody
蛋白名称
Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q14872
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14872/entry
Mouse Swissprot No.
Q07243
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q07243
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
MTF1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Translocation to the nucleus is induced by metals. .
功能
function:Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).,similarity:Contains 6 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.