产品名称
SOX13 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9580
Human Swissprot No.
Q9UN79
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UN79/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20668
Mouse Swissprot No.
Q04891
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q04891
免疫原
Synthesized peptide derived from human SOX13 AA range: 561-611
特异性
This antibody detects endogenous levels of SOX13 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008],
组织表达
Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level) (PubMed:10871192). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver (PubMed:10871192, PubMed:20028982). Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, spleen, testicle, thymus and thyroid (PubMed:20028982).
细胞定位
Nucleus . Cytoplasm .
功能
function:Binds to the sequence 5'-AACAAT-3'.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Highly expressed in kidney, lung, and liver and low expression in thymus, brain, spleen, and muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
