产品名称
XPO6 Rabbit Polyclonal Antibody
基因名称
XPO6 KIAA0370 RANBP20
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23214
Human Swissprot No.
Q96QU8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96QU8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74204
Mouse Swissprot No.
Q924Z6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q924Z6
免疫原
Synthesized peptide derived from human XPO6 AA range: 204-254
特异性
This antibody detects endogenous levels of XPO6 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012],
细胞定位
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm. .
功能
function:Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.,similarity:Belongs to the exportin family.,similarity:Contains 1 importin N-terminal domain.,subcellular location:Shuttles between the nucleus and the cytoplasm.,subunit:Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with ACTB. Interacts with ACTB in a RanGTP-dependent manner.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
