产品名称
FHL3 Rabbit Polyclonal Antibody
蛋白名称
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q13643
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13643/entry
Mouse Swissprot No.
Q9R059
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R059
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
FHL3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
组织表达
Expressed only in skeletal muscle.
细胞定位
Nucleus . Cytoplasm .
功能
similarity:Contains 3 LIM zinc-binding domains.,similarity:Contains 4 LIM zinc-binding domains.,tissue specificity:Expressed only in skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
