产品名称
DET1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55070
Human Swissprot No.
Q7L5Y6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7L5Y6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/76375
Mouse Swissprot No.
Q9D0A0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D0A0
免疫原
Synthesized peptide derived from human DET1 AA range: 48-98
特异性
This antibody detects endogenous levels of DET1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Highly expressed in the ovary, some lymphoid organs and resting leukocytes.
功能
function:Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.,similarity:Belongs to the DET1 family.,subunit:Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1.,tissue specificity:Highly expressed in the ovary, some lymphoid organs and resting leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
