产品名称
TXND8 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/255220
Human Swissprot No.
Q6A555
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6A555/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67402
Mouse Swissprot No.
Q69AB2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q69AB2
Rat Gene Link
https://www.uniprot.org/uniprot/362525
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q69AB1
免疫原
Synthesized peptide derived from human TXND8 AA range: 64-114
特异性
This antibody detects endogenous levels of TXND8 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).
细胞定位
Cytoplasm . Golgi apparatus .
功能
function:May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.,miscellaneous:Increased levels, possibly caused by overexpression, are observed in morphologically abnormal spermatozoa from infertile men, suggesting that it may be used as a marker of aberrant spermatogenesis.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
