产品名称
FIBP Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9158
Human Swissprot No.
O43427
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O43427/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/58249
Mouse Swissprot No.
Q9JI19
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JI19
免疫原
Synthesized peptide derived from human FIBP AA range: 104-154
特异性
This antibody detects endogenous levels of FIBP at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney.
细胞定位
Nucleus. Endomembrane system; Peripheral membrane protein. Also associated with cytoplasmic membranes, particularly of mitochondria.
功能
function:May be involved in mitogenic function of FGF1.,subcellular location:Also associated with cytoplasmic membranes, particularly of mitochondria.,subunit:Binds to internalized FGF1.,tissue specificity:Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.