产品名称
SC6A9 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6536
Human Swissprot No.
P48067
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P48067/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/14664
Mouse Swissprot No.
P28571
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P28571
Rat Gene Link
https://www.uniprot.org/uniprot/116509
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P28572
免疫原
Synthesized peptide derived from human SC6A9 AA range: 101-151
特异性
This antibody detects endogenous levels of SC6A9 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. [provided by RefSeq, Jun 2016],
组织表达
Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:All GLYT-1 subtypes can be found in brain, kidney, pancreas, lung, placenta, liver. But GLYT-1C subtype is only found in the brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
