产品名称
T2FA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2962
Human Swissprot No.
P35269
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P35269/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/98053
Mouse Swissprot No.
Q3THK3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3THK3
Rat Gene Link
https://www.uniprot.org/uniprot/316123
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AY96
免疫原
Synthesized peptide derived from human T2FA AA range: 462-512
特异性
This antibody detects endogenous levels of T2FA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
功能
caution:Was reported (PubMed:10428810) to have a protein kinase activity and to autophosphorylates on Ser-385 and Thr-389.,function:TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.,PTM:Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.,similarity:Belongs to the TFIIF alpha subunit family.,subunit:Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2 and CTDP1. Interacts with TAF6/TAFII80.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.