产品名称
NOVA2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4858
Human Swissprot No.
Q9UNW9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UNW9/entry
免疫原
Synthesized peptide derived from human NOVA2 AA range: 274-324
特异性
This antibody detects endogenous levels of NOVA2 at Human
宿主
Polyclonal, Rabbit,IgG
组织表达
Brain. Expression restricted to astrocytes.
功能
disease:Autoantigen in the paraneoplastic opsoclonus myoclonus ataxia (POMA), a paraneoplastic neurological syndrome/disorder (PNS/D) associated with breast cancer, fallopian cancer, and SCLCa and characterized primarily by loss of inhibitory control of motor neurons in the spinal cord and brainstem. Recognized by the IgG autoantibody ANNA-2 (also called anti-Ri).,domain:The third KH domain (KH3) recognizes specifically 5'-UCAY-3'.,function:May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.,similarity:Contains 3 KH domains.,subunit:Interacts with PTBP2.,tissue specificity:Brain. Expression restricted to astrocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
