产品名称
DMP4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/56975
Human Swissprot No.
Q8IXL6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IXL6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/80752
Mouse Swissprot No.
Q5MJS3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5MJS3
免疫原
Synthesized peptide derived from human DMP4 AA range: 328-378
特异性
This antibody detects endogenous levels of DMP4 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Apr 2014],
细胞定位
Secreted . Golgi apparatus .
功能
disease:Defects in FAM20C are the cause of Raine syndrome (RNS) [MIM:259775]. RNS is an autosomal recessive osteosclerotic bone dysplasia with neonatal lethal outcome. Clinical features include generalized osteosclerosis, craniofacial dysplasia and microcephaly.,function:Calcium-binding protein which may play a role in dentin mineralization.,similarity:Belongs to the FAM20 family.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
