产品名称
GKN1 Rabbit Polyclonal Antibody
基因名称
GKN1 AMP18 CA11 UNQ489/PRO1005
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/56287
Human Swissprot No.
Q9NS71
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NS71/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/66283
Mouse Swissprot No.
Q9CR36
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CR36
免疫原
Synthesized peptide derived from human GKN1 AA range: 47-97
特异性
This antibody detects endogenous levels of GKN1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008],
组织表达
Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines.
细胞定位
Secreted . Cytoplasmic granule . Golgi apparatus . Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. .
功能
caution:It is uncertain whether Met-1 or Met-15 is the initiator.,function:Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.,similarity:Belongs to the gastrokine family.,similarity:Contains 1 BRICHOS domain.,tissue specificity:Expressed in stomach. No expression is detected in cancer tissue or gastric cancer cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
