产品名称
FIZ1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/84922
Human Swissprot No.
Q96SL8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96SL8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/23877
Mouse Swissprot No.
Q9WTJ4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WTJ4
免疫原
Synthesized peptide derived from human FIZ1 AA range: 141-191
特异性
This antibody detects endogenous levels of FIZ1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus .
功能
function:May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.,similarity:Contains 11 C2H2-type zinc fingers.,subunit:Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and PDGFR. Interacts with NRL.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
