产品名称
PLP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5355
Human Swissprot No.
Q04941
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q04941/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18824
Mouse Swissprot No.
Q9R1Q7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R1Q7
Rat Gene Link
https://www.uniprot.org/uniprot/302562
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P742
免疫原
Synthesized peptide derived from human PLP2 AA range: 56-106
特异性
This antibody detects endogenous levels of PLP2 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010],
组织表达
Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:May play a role in cell differentiation in the intestinal epithelium.,similarity:Contains 1 MARVEL domain.,tissue specificity:Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
