产品名称
ZEP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3097
Human Swissprot No.
P31629
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P31629/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/15273
Mouse Swissprot No.
Q3UHF7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UHF7
Rat Gene Link
https://www.uniprot.org/uniprot/29721
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q00900
免疫原
Synthesized peptide derived from human ZEP2 AA range: 1975-2025
特异性
This antibody detects endogenous levels of ZEP2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012],
组织表达
Expressed in brain and skeletal muscle.
功能
function:This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.,induction:By mitogens and phorbol ester.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with TCF4.,tissue specificity:Expressed in brain and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
